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Free whitepaper available to download!

You can now download our latest whitepaper – A novel phenotypic screening platform targeting chronic pain drug discovery

Chronic pain is a disease area with a significant and unmet need for improved treatments. However, due to the complex nature of pain transduction, pain is a notoriously difficult area for drug discovery, where conventional target-based efforts have largely failed to produce new drugs.

In this whitepaper, we present a novel phenotypic screening cascade based on our proprietary Cellaxess® Elektra technology. This cascade provides an exciting opportunity to efficiently identify new classes of compounds that affect neuronal excitability in primary peripheral pain-sensing neurons, while sparing the CNS and cardiovascular system. Important decisions about which compounds to advance to further testing and which to eliminate can be made in a seamless operation much earlier along the discovery process.