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Cellaxess® technology


Cellectricons Cellaxess technology is a refined electroporation method for targeted delivery to a wide range of biologically relevant cell types including primary cells and cells traditionally considered hard to transfect. In addition, the technology is ideally suited for high quality transfection in tissue slices and in-vivo explants. The method is based on a patented capillary electroporation concept where agents and focused electric fields are delivered simultaneously to a cell culture. Capillary electroporation is highly efficient because of excellent spatial, temporal and fluidic control. Cellaxess can be used for introduction of all types of molecules, ranging in size from target-designed dyes, to oligonucleotides, and large plasmids, and if desired, read-out can be performed within seconds after transfection.

Besides from transfection, the Cellaxess technology is ideally suited for siRNA screening studies to study the function of a specific protein, or the interdependencies between a specific function and a cluster of proteins. Other applications are intracellular target screening where receptor/ ligand studies can be conducted on an intracellular protein in a cell-based assay format.