The Dynaflow Pro II System turns your existing patch clamp rig into a flexible electrophysiology system compatible with any cell type, any receptor and any patch clamp configuration. The Dynaflow system can be used for all kinds of ion channel research ranging from pharmacology to novel approaches in biotechnology. Dynaflow enables fast and complete solution exchange (ms) with low consumption of compounds (µl).




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[hERG drug application comparison]
[Binding properties of the 5HT3 receptor]
[hERG safety pharmacology screening]
[Structure analysis of KATP channel]
[GABAA high content recordings]
[Glutamate positive modulation]
[hKv4.3 antiarrhythmic compound inhibition]
[NMDA currents in acutely isolated neurons]
[ACh multiple compound analysis]
[Typical dose response experiment]
[Sophisticated characterization of P2X7 antagonists]
[Temperature dependent hERG inhibition]
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See Dynaflow in action.
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Animation
(WMV, 7MB)

See the operating principles of Dynaflow microfluidic chips.
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Experience true versatility and reliability

Gigaseal recordings with low variation and high reproducibility.

Use any cell type, any receptor, and any patch-clamp configuration.

Versatility - from mechanistic receptor studies to secondary screening.

Single use chips - no cleaning and no risk of cross-contamination.

Low consumption of compounds (µl).
High-throughput and maximized data quality

Numerous cells per chip.

Multiple compound analyses per chip.

Full dose-response for every compound.

More pharmacologically relevant data per day.
Chips optimized for safety pharmacology

Enables long experiments and long exposure times.

Optimized for sticky compounds.

Designed for cumulative dose-response.

Dynaflow Temperature Control System››

Experimental freedom - facilitating complex assays

Rapid solution exchange enables analysis of fast kinetics.

Complete control over cell and exposure times.

Online protocol changes.